Will and Jake Grimm are traveling Confidence trick who arrive in French Revolutionary Wars Germany during the early 19th century. They ride into the town Karlstadt am Main to rid the town of a witch's ghost. However, after killing the "ghost", it is revealed that the Brothers Grimm have actually set up fake demons and monsters to trick the village. Afterwards, as they are celebrating at an inn, Italian torturer Cavaldi takes them to the French General Delatombe. Delatombe forces them to solve a mystery: the girls of the small village of Marbaden are going missing and the villagers are convinced that supernatural beings are responsible. The Brothers are charged with finding out who is responsible, under the assumption that it is the work of con artists like themselves. However, they soon discover that it is in fact the work of a real supernatural force: a beautiful, yet dangerous, 500-year-old, Thuringia Queen stealing young girls to restore her own beauty.