Will Stronghold begins ninth grade at Sky High, a high school that exclusively teaches teenagers with superpowers. Will's parents are The Commander and Jetstream, two of the world's most famous superheroes. Will's best friend, Layla, who happens to have a crush on him, has the power to manipulate plant life. Will is anxious about attending Sky High, located on a floating campus reached by a flying school bus, because, unbeknownst to his parents, he has not developed any super powers.