Wren is a physician and activist working in West Africa with the organization Médecins du Monde that her dead father started so many years ago. She's happy to lead the organization, but frequently finds herself negatively comparing herself to her father's achievements. During 2003 Wren meets Miguel, a handsome surgeon who has also devoted himself to treating people from impoverished and war torn sections of the world. The two fall in love, however Wren soon discovers that Miguel has had a prior sexual relationship with her cousin, which contributes to the decay of their relationship.