The film tells the story of Jon Aldrich (Tom Selleck), a successful stockbroker who is living a good life with a wife and kids until he comes across his elderly father who has major dementia and, as a result of it, wreaks all kinds of havoc on his life including his own, which among all of them involves accidentally burning down his own house. Jon tries to get his sister, Arlene (Christine Ebersole) (who has two sons of her own but is an irresponsible gold digger), to take care of their parents, but she won't even open the door. As a result, his father, Harry (Don Ameche), and his mother, Mildred (Anne Jackson), have to move in with him and his family. That is the moment that his good life starts going downhill.