Set in New York City, the film focuses on the relationship between two people as they await the end of all life on Earth. Scientists and theologians alike have predicted that by the next morning at 4:44 a.m. Eastern Standard Time deadly solar and cosmic radiation will destroy the Earth's protective ozone layer, and along with it, all life on the planet. Mixed in throughout the film are news clips of various reporters, commentators and celebrities who contemplate what the end of the world will be like.